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BREAKING
Information Minister in Pakistani-administered Kashmir: Five civilians killed and at least 29 others injured in shelling across the border with India
Israeli Army Radio's diplomatic correspondent quoted a senior Israeli official as saying: So he [Trump] decided to cut off contact. That might still change, but that’s the situation right now
Israeli Army Radio's diplomatic correspondent quoted a senior Israeli official as saying: Trump’s circle told him [Dermer] that Netanyahu was manipulating him, and there’s nothing Trump hates more than being portrayed as someone being played
Senior Palestinian official to Al Mayadeen: Meetings between the Israelis, Egyptians, and Qataris are all centered around the Israeli proposal, which does not guarantee an end to the war [on Gaza]
Senior Palestinian official to Al Mayadeen: “Israel” is threatening to expand the ground offensive if Hamas rejects the proposal
Senior Palestinian official to Al Mayadeen: Hamas rejects the Israeli proposal, viewing it as failing to guarantee an end to the war
Senior Palestinian official to Al Mayadeen: “Israel” is sticking to its proposal, and insists there is no alternative offer on the table for negotiation
Senior Palestinian official to Al Mayadeen: The meetings between the Israelis and the Egyptians and Qataris all revolve around the Israeli proposal
The administration was clearly looking for an off-ramp for this campaign against Ansar Allah, NBC News reports, citing US official
Trump's operation against Ansar Allah cost more than $1 billion, NBC News reports, citing US official

Study analyzes 18,000+ cancer samples, finds new mutation patterns

  • By Al Mayadeen Net
  • Source: Agencies
  • 22 Apr 2022 11:49
2 Min Read

Researchers analyzed 19 different types of cancer samples and identified 58 new clues to the causes of cancer called “mutational signatures”.

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  • The study unprecedently performed a huge comprehensive “whole genome” analysis of cancer samples
    The study unprecedently performed a huge comprehensive “whole genome” analysis of cancer samples

A study published Thursday in the journal Science analyzed the full genetic blueprints of more than 18,000 cancer samples, and found new mutation patterns, which could help doctors provide better treatment, the Associated Press reported.

According to AP, the study unprecedently performed a huge comprehensive “whole genome” analysis of cancer samples.

“This is the largest cohort in the world. It is extraordinary,” underscored Serena Nik-Zainal of the University of Cambridge, who was part of the team.

Genetic sequencing technology

AP explained that "researchers were able to analyze such a large number because of the same improvements in genetic sequencing technology that recently allowed scientists to finally finish decoding the entire human genome – more capable, accurate machines."

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Andrew Futreal, a genomic medicine expert at MD Anderson Cancer Center in Houston, considered that “We can really begin to tease out the underpinnings of the erosive sort of forces that go to sort of generate cancer."

Understanding each person’s cancer more precisely

Cancer occurs when changes in a person’s DNA cause cells to grow and divide uncontrollably. In 2020, there were about 19 million new cancer cases worldwide, reported AP.

The researchers analyzed 19 different types of cancer samples and identified 58 new clues to the causes of cancer called “mutational signatures”. Nik-Zainal said the researchers confirmed 51 of more than 70 previously reported mutation patterns.

According to AP, "Some arise because of problems within a person’s cells; others are sparked by environmental exposures such as ultraviolet radiation, tobacco smoke or chemicals."

Nik-Zainal pointed out that knowing more mutation patterns “helps us to understand each person’s cancer more precisely” and helps guide their treatment.

Making use of the information

To allow doctors to make use of such information, "researchers developed a computer algorithm that will allow them to find common mutation patterns and seek out rare ones," AP said.

Futreal explained that "the data can also show doctors what tends to happen over time when a patient develops a cancer with a certain mutation pattern — helping them intervene earlier and hopefully stop the developing disease in its tracks," AP mentioned.

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  • Cambridge
  • Cancer
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  • houston

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