Al Mayadeen English

  • Ar
  • Es
  • x
Al Mayadeen English

Slogan

  • News
    • Politics
    • Economy
    • Sports
    • Arts&Culture
    • Health
    • Miscellaneous
    • Technology
    • Environment
  • Articles
    • Opinion
    • Analysis
    • Blog
    • Features
  • Videos
    • NewsFeed
    • Video Features
    • Explainers
    • TV
    • Digital Series
  • Infographs
  • In Pictures
  • • LIVE
News
  • Politics
  • Economy
  • Sports
  • Arts&Culture
  • Health
  • Miscellaneous
  • Technology
  • Environment
Articles
  • Opinion
  • Analysis
  • Blog
  • Features
Videos
  • NewsFeed
  • Video Features
  • Explainers
  • TV
  • Digital Series
Infographs
In Pictures
  • Africa
  • Asia
  • Asia-Pacific
  • Europe
  • Latin America
  • MENA
  • Palestine
  • US & Canada
BREAKING
Al Mayadeen's correspondent in Gaza: The tower destroyed by the Israeli occupation in Gaza includes media offices, including Al Mayadeen's bureau.
Al Mayadeen's correspondent in Gaza: Four fetuses and three premature babies died at Nasser Medical Complex due to malnutrition
Lebanese Ministry of Health: One person was killed in an Israeli airstrike on a car in the town of Burj Qalawieh, south Lebanon.
Al Mayadeen correspondent: The first ship of the Maghreb fleet delivering aid to break the siege on Gaza departs from the port of Gammarth in Tunisia.
Channel 12: Airspace closed at Ramon Airport due to fears of drone infiltration
IOF Spokesperson: Sirens sounded over an aircraft infiltration in the Bir Ora area, and details are being examined
Drone infiltration sirens sound north of the Gulf of Aqaba
Al Mayadeen's correspondent in Gaza: The Israeli occupation carried out five extremely violent raids on the western areas of Gaza City
Al Mayadeen's correspondent in Gaza: The Israeli occupation carried out major bombings in the Gaza Strip, the most violent since October 7
Yemeni Armed Forces spokesperson Brigadier General Yahya Saree: The missile force carried out a major operation using the Palestine 2 ballistic hypersonic missile, hitting several targets in occupied Yafa.

New drug could stop breast cancer variant from returning by 25%

  • By Al Mayadeen English
  • Source: News Websites
  • 2 Jun 2023 18:15
4 Min Read

Thousands of women with the world's most prevalent form of breast cancer might benefit from a medicine that reduces their chances of relapse by a quarter.

  • x
  •  A radiologist uses a magnifying glass to check mammograms for breast cancer in Los Angeles, May 6, 2010 (AP Photo/Damian Dovarganes, File)
    A radiologist uses a magnifying glass to check mammograms for breast cancer in Los Angeles, May 6, 2010 (AP Photo/Damian Dovarganes, File)

Thousands more women with the world's most prevalent form of breast cancer might benefit from an innovative medicine that extends their lives and reduces their chances of relapse by a quarter.

Every year, more than 2 million women are diagnosed with the illness, which is the most common cancer in the world. Despite advances in treatment in recent decades, many individuals may experience cancer recurrence. If a recurrence occurs, it is usually at a later stage.

A promising study was revealed at the world's biggest cancer conference, the American Society of Clinical Oncology (Asco), indicating that ribociclib, a novel targeted treatment medicine, might be a game changer. According to trial data, it can improve survival and dramatically reduce the likelihood of cancer recurrence.

Ribociclib has previously been proven to improve survival in people with advanced breast cancer. However, researchers observed in a recent study that it may also improve outcomes for people with much earlier-stage illnesses, such as in the case where cancer has not yet reached lymph nodes.

The findings piqued the interest of researchers and oncologists at Asco's annual meeting in Chicago since the evidence shows that the medicine, also known as Kisqali, might prevent cancer from returning in a large population and influence global practice.

Ribociclib is a small molecule inhibitor, which is a type of targeted treatment. It acts by targeting CDK4 and CDK6 proteins in breast cancer cells, which regulate cell proliferation, including cancer cell growth.

The medicine reduced the chance of recurrence by 25% when administered in conjunction with normal hormone therapy compared to hormone therapy alone following traditional therapies, according to a late-stage experiment, and has been licensed by authorities in the UK and the US. 

Because of the large number of people it potentially aids, the earlier-stage setting, when tumors can still be surgically removed, is considered a far greater breakthrough.

Patients with breast cancer are often offered surgery, chemotherapy, or radiation treatment before being prescribed hormone-blocking medicines to try to prevent the illness from reoccurring.

Related News

Russia completes preclinical trials of cancer vaccine, seeks approval

Biden diagnosed with 'aggressive' prostate cancer

The study discovered that combining ribociclib with hormone treatment resulted in a "significant improvement" in disease-free survival durations for patients with hormone receptor-positive, HER2-negative early-stage breast cancer.

Hormone receptor-positive, HER2-negative breast cancer is the most common subtype of the disease, making up nearly 70% of all breast cancer cases in the US.

According to lead author Dr. Dennis Slamon, “Currently, approved targeted treatments can only be used in a small population of patients diagnosed with hormone receptor-positive, HER2-negative early breast cancer, leaving many without an effective treatment option for reducing risk of the cancer returning."

Slamon explained that nearly one-third of people with stage two hormone receptor-positive HER2-negative will have a relapse after treatment and more than half with stage 3 will have the cancer make a full return.

“Thus, there is a significant unmet need for both reducing the risk of recurrence and providing a tolerable treatment option that keeps patients cancer-free without disrupting their daily life.”

The Natalee study involved 5,101 patients who were given either ribociclib for three years alongside five years of hormonal therapy or the hormonal therapy alone.

After three years, 90.4% of those taking ribociclib remained free of disease, compared with 87.1% in the hormonal therapy alone group. Ribociclib also showed more favorable outcomes in overall survival, recurrence-free survival, and distant disease-free survival, according to the researchers.

Dr. Rita Nanda, an Asco expert in Chicago, stated that the results suggest " there will be a role for adjuvant ribociclib for stage two and higher hormone receptor-positive, HER2-negative breast cancer,”

Dr Catherine Elliott, director of research and partnerships at Cancer Research UK called the findings "promising" although more research is needed.

“The combination of ribociclib and hormonal therapy could provide a new treatment option for people with this type of early-stage breast cancer, reducing the risk of the disease coming back and improving survival.”

  • Breast cancer
  • Cancer

Most Read

The damaged building in the Katara neighborhood, Doha, Qatar, September 9, 2025 (Social media)

Hamas delegation survives Israeli assassination attempt in Qatar

  • Politics
  • 9 Sep 2025
Pro-"Israel" conservative Charlie Kirk shot during Utah speech

American far-right activist Charlie Kirk shot dead during Utah speech

  • US & Canada
  • 11 Sep 2025
Uprising against Volker Turk at the Human Rights Council over Gaza.

Uprising against Volker Turk at the Human Rights Council over Gaza

  • Politics
  • 12 Sep 2025
A screengrab from the ad played on Fox News. (X Screengrab)

Fox airs ad warning Trump not to let Netanyahu 'play' him on Gaza

  • US & Canada
  • 11 Sep 2025

Coverage

All
The Ummah's Martyrs

Read Next

All
Australia warned of deadly climate risks in landmark report
Environment

Millions at risk from rising seas, extreme heat in Australia: Report

DPRK leader Kim Jong Un inspects a new weapons factory in undisclosed location, Democratic People's Republic of Korea, August 31, 2025 (AP)
Politics

DPRK defies US, says nuclear state status 'permanently enshrined'

Soldier F faces trial over bloody Sunday killings after 53 years
Miscellaneous

British Soldier F faces trial over Bloody Sunday killings after 53 yrs

Pro-Palestinian protesters demonstrate at the University of Sydney to protest the Israel Hamas war, Wednesday, April 24, 2024 (AP)
Politics

Protest outside ABC decries media silence on Gaza journalist killings

Al Mayadeen English

Al Mayadeen is an Arab Independent Media Satellite Channel.

All Rights Reserved

  • x
  • Privacy Policy
  • About Us
  • Contact Us
  • Authors
Android
iOS