Al Mayadeen English

  • Ar
  • Es
  • x
Al Mayadeen English

Slogan

  • News
    • Politics
    • Economy
    • Sports
    • Arts&Culture
    • Health
    • Miscellaneous
    • Technology
    • Environment
  • Articles
    • Opinion
    • Analysis
    • Blog
    • Features
  • Videos
    • NewsFeed
    • Video Features
    • Explainers
    • TV
    • Digital Series
  • Infographs
  • In Pictures
  • • LIVE
News
  • Politics
  • Economy
  • Sports
  • Arts&Culture
  • Health
  • Miscellaneous
  • Technology
  • Environment
Articles
  • Opinion
  • Analysis
  • Blog
  • Features
Videos
  • NewsFeed
  • Video Features
  • Explainers
  • TV
  • Digital Series
Infographs
In Pictures
  • Africa
  • Asia
  • Asia-Pacific
  • Europe
  • Latin America
  • MENA
  • Palestine
  • US & Canada
BREAKING
Hamas official says despite this, Hamas leadership is currently undertaking a thorough review of the new proposal
Hamas official says the response fails to meet any of the just and legitimate demands of our people
Hamas official says it is clear that the Israeli response fundamentally seeks to entrench the occupation
Reuters citing Hamas official: Group received Israeli response to Witkoff proposal
Sources to Al Mayadeen: The news regarding a press conference tonight by the head of the Hamas movement in the Gaza Strip, Khalil Al-Hayya, is false.
Lebanese Ministry of Health: One person was martyred in an Israeli drone strike on the outskirts of Nabatieh al-Fawqa
Al Mayadeen's correspondent: The death toll in the al-Bureij camp massacre has risen to 19
Nicolas Maduro: Maria Corina Machado and imperialism wanted to spread violence and chaos so there would be no elections.
Venezuelan President Nicolás Maduro: We were able to neutralize 60 attacks on oil refineries and oil facilities and arrest more than 70 individuals involved.
CNN citing sources: Talks between Washington and Tehran are close to reaching a comprehensive agreement that could be concluded during the next meeting.

New drug could stop breast cancer variant from returning by 25%

  • By Al Mayadeen English
  • Source: News Websites
  • 2 Jun 2023 18:15
4 Min Read

Thousands of women with the world's most prevalent form of breast cancer might benefit from a medicine that reduces their chances of relapse by a quarter.

  • x
  •  A radiologist uses a magnifying glass to check mammograms for breast cancer in Los Angeles, May 6, 2010 (AP Photo/Damian Dovarganes, File)
    A radiologist uses a magnifying glass to check mammograms for breast cancer in Los Angeles, May 6, 2010 (AP Photo/Damian Dovarganes, File)

Thousands more women with the world's most prevalent form of breast cancer might benefit from an innovative medicine that extends their lives and reduces their chances of relapse by a quarter.

Every year, more than 2 million women are diagnosed with the illness, which is the most common cancer in the world. Despite advances in treatment in recent decades, many individuals may experience cancer recurrence. If a recurrence occurs, it is usually at a later stage.

A promising study was revealed at the world's biggest cancer conference, the American Society of Clinical Oncology (Asco), indicating that ribociclib, a novel targeted treatment medicine, might be a game changer. According to trial data, it can improve survival and dramatically reduce the likelihood of cancer recurrence.

Ribociclib has previously been proven to improve survival in people with advanced breast cancer. However, researchers observed in a recent study that it may also improve outcomes for people with much earlier-stage illnesses, such as in the case where cancer has not yet reached lymph nodes.

The findings piqued the interest of researchers and oncologists at Asco's annual meeting in Chicago since the evidence shows that the medicine, also known as Kisqali, might prevent cancer from returning in a large population and influence global practice.

Ribociclib is a small molecule inhibitor, which is a type of targeted treatment. It acts by targeting CDK4 and CDK6 proteins in breast cancer cells, which regulate cell proliferation, including cancer cell growth.

The medicine reduced the chance of recurrence by 25% when administered in conjunction with normal hormone therapy compared to hormone therapy alone following traditional therapies, according to a late-stage experiment, and has been licensed by authorities in the UK and the US. 

Because of the large number of people it potentially aids, the earlier-stage setting, when tumors can still be surgically removed, is considered a far greater breakthrough.

Patients with breast cancer are often offered surgery, chemotherapy, or radiation treatment before being prescribed hormone-blocking medicines to try to prevent the illness from reoccurring.

Related News

Biden diagnosed with 'aggressive' prostate cancer

Senate report reveals Trump slashed cancer research by 31%

The study discovered that combining ribociclib with hormone treatment resulted in a "significant improvement" in disease-free survival durations for patients with hormone receptor-positive, HER2-negative early-stage breast cancer.

Hormone receptor-positive, HER2-negative breast cancer is the most common subtype of the disease, making up nearly 70% of all breast cancer cases in the US.

According to lead author Dr. Dennis Slamon, “Currently, approved targeted treatments can only be used in a small population of patients diagnosed with hormone receptor-positive, HER2-negative early breast cancer, leaving many without an effective treatment option for reducing risk of the cancer returning."

Slamon explained that nearly one-third of people with stage two hormone receptor-positive HER2-negative will have a relapse after treatment and more than half with stage 3 will have the cancer make a full return.

“Thus, there is a significant unmet need for both reducing the risk of recurrence and providing a tolerable treatment option that keeps patients cancer-free without disrupting their daily life.”

The Natalee study involved 5,101 patients who were given either ribociclib for three years alongside five years of hormonal therapy or the hormonal therapy alone.

After three years, 90.4% of those taking ribociclib remained free of disease, compared with 87.1% in the hormonal therapy alone group. Ribociclib also showed more favorable outcomes in overall survival, recurrence-free survival, and distant disease-free survival, according to the researchers.

Dr. Rita Nanda, an Asco expert in Chicago, stated that the results suggest " there will be a role for adjuvant ribociclib for stage two and higher hormone receptor-positive, HER2-negative breast cancer,”

Dr Catherine Elliott, director of research and partnerships at Cancer Research UK called the findings "promising" although more research is needed.

“The combination of ribociclib and hormonal therapy could provide a new treatment option for people with this type of early-stage breast cancer, reducing the risk of the disease coming back and improving survival.”

  • Breast cancer
  • Cancer

Most Read

US judges quietly consider private security amid Trump tensions

US judges quietly consider private security amid Trump pressures

  • US & Canada
  • 25 May 2025
Rep. Randy Fine, R-Palm Bay, answers a question about his House Bill 3-C: Independent Special Districts in the House of Representatives April 20, 2022, at the Capitol in Tallahassee, Florida (AP/Phil Sears)

GOP lawmaker says Gaza needs same end as WWII Japan, with nukes

  • MENA
  • 23 May 2025
President Donald Trump and Israeli Prime Minister Benjamin Netanyahu arrive to a news conference in the East Room of the White House, Tuesday, Feb. 4, 2025, in Washington (AP)

Rift widens: Trump, Netanyahu clash in heated phone call over Iran

  • Politics
  • 26 May 2025
Iran advisor reveals details of US-Iran nuclear talks to Al Mayadeen

Iran advisor reveals details of US-Iran nuclear talks: Al Mayadeen

  • MENA
  • 24 May 2025

Coverage

All
War on Gaza

Read Next

All
Palestinians cross from the Israeli military Qalandia checkpoint near the West Bank city of Ramallah to occupied al-Quds on Friday, March 14, 2025 (AP)
Politics

Israeli regime arrests martyr Walid Daqqa's wife Sanaa

Spokesperson for the Yemeni Armed Forces, Brigadier General Yahya Saree, announces a new operation against Ben Gurion Airport on May 29, 2025 (Yemeni Military Media)
Politics

Yemen announces successful hypersonic missile strike on Ben Gurion

An Israeli army vehicle moves in the Gaza Strip as seen from southern occupied Palestine, Thursday, May 29, 2025 (AP)
Politics

Hamas rejects Witkoff ceasefire plan, says alters terms

Iranian Foreign Minister Abbas Araghchi attends a news conference following his meeting with Russian Foreign Minister Sergey Lavrov in Moscow, Russia, Friday, April 18, 2025 (AP)
Politics

Iran denounces media speculation, reaffirms conditions for any US deal

Al Mayadeen English

Al Mayadeen is an Arab Independent Media Satellite Channel.

All Rights Reserved

  • x
  • Privacy Policy
  • About Us
  • Contact Us
  • Authors
Android
iOS